NETO1 Antikörper (C-Term)

Produktnummer ABIN6991577

Produktdetails anti-NETO1 Antikörper

Target: NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))

Bindungsspezifität: AA 350-400, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NETO1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: NETO1 antibody is predicted to not cross-react with other NETO protein family members.

Aufreinigung: NETO1 Antibody is affinity chromatography purified via peptide column.

Immunogen: NETO1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human NETO1. The immunogen is located within amino acids 350 - 400 of NETO1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NETO1 antibody can be used for detection of NETO1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NETO1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NETO1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu NETO1

Target: NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))

Andere Bezeichnung: NETO1 (NETO1 Produkte)

Synonyme: BCTL1 antikoerper, BTCL1 antikoerper, AI851453 antikoerper, Btcl1 antikoerper, C130005O10Rik antikoerper, RGD1566269 antikoerper, neuropilin and tolloid like 1 antikoerper, neuropilin (NRP) and tolloid (TLL)-like 1 antikoerper, NETO1 antikoerper, Neto1 antikoerper

Hintergrund: NETO1 Antibody: Neuropilin and tolloid-like protein 1 (NETO1) is involved in the development and/or maintenance of neuronal circuitry. It is a type I transmembrane protein that is expressed in the brain and retina. NETO1 contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. It has three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue. Furthermore, as an accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR), it regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.

Molekulargewicht: Predicted: 60 kDa

Observed: 60 kDa

Gen-ID: 81832

NCBI Accession: NP_694821

UniProt: Q8TDF5

Pathways: Regulation of long-term Neuronal Synaptic Plasticity