TMEM88 Antikörper (C-Term)

Produktnummer ABIN6991552

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TMEM88 in ELISA, WB, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für TMEM88 Antikörper (C-Term) (ABIN6991552)

Target: TMEM88 (Transmembrane Protein 88 (TMEM88))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM88 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TMEM88 Antikörper

Bindungsspezifität: AA 110-160, C-Term

Spezifität: At least two isoforms of TMEM88 are known to exist, this antibody will recognize both isoforms.

Aufreinigung: TMEM88 Antibody is affinity chromatography purified via peptide column.

Immunogen: TMEM88 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TMEM88. The immunogen is located within amino acids 110 - 160 of TMEM88.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TMEM88 antibody can be used for detection of TMEM88 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TMEM88 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TMEM88 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TMEM88

Target: TMEM88 (Transmembrane Protein 88 (TMEM88))

Andere Bezeichnung: TMEM88

Hintergrund: TMEM88 Antibody: Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.

Gen-ID: 92162

UniProt: Q6PEY1