Translin Antikörper (C-Term)

Produktnummer ABIN6991538

Der Kaninchen Polyklonal Anti-Translin-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, Translin in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Translin Antikörper (C-Term) (ABIN6991538)

Target: Translin (TSN)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Translin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Translin Antikörper

Bindungsspezifität: C-Term

Spezifität: At least two isoforms of Translin are known to exist, this antibody will detect both.

Aufreinigung: Translin Antibody is affinity chromatography purified via peptide column.

Immunogen: Translin antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human Translin. The immunogen is located within the last 50 amino acids of Translin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Translin antibody can be used for detection of Translin by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Translin Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Translin antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Translin

Target: Translin (TSN)

Andere Bezeichnung: Translin

Hintergrund: Translin Antibody: Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.

Gen-ID: 7247

NCBI Accession: NP_004613

UniProt: Q15631