LRRTM2 Antikörper (C-Term)

Produktnummer ABIN6991482

Dieses Anti-LRRTM2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LRRTM2 in WB, ELISA, IHC (p) und IF. Geeignet für Human, Ratte und Maus.

Kurzübersicht für LRRTM2 Antikörper (C-Term) (ABIN6991482)

Target: LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRTM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-LRRTM2 Antikörper

Bindungsspezifität: C-Term

Spezifität: LRRTM2 antibody is predicted to not cross-react with other LRRTM family members.

Aufreinigung: LRRTM2 Antibody is affinity chromatography purified via peptide column.

Immunogen: LRRTM2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRTM2. The immunogen is located within the last 50 amino acids of LRRTM2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LRRTM2 antibody can be used for detection of LRRTM2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LRRTM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LRRTM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LRRTM2

Target: LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))

Andere Bezeichnung: LRRTM2

Hintergrund: LRRTM2 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development.

Gen-ID: 26045

UniProt: O43300

Pathways: Synaptic Membrane