ZBTB5 Antikörper (C-Term)

Produktnummer ABIN6991469

Der Kaninchen Polyklonal anti-ZBTB5 Antikörper wird verwendet zum Nachweis von ZBTB5 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC (p) und IF.

Kurzübersicht für ZBTB5 Antikörper (C-Term) (ABIN6991469)

Target: ZBTB5 (Zinc Finger and BTB Domain Containing 5 (ZBTB5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-ZBTB5 Antikörper

Bindungsspezifität: C-Term

Spezifität: At least two isoforms of ZBTB5 are known to exist, this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.

Aufreinigung: ZBTB5 Antibody is affinity chromatography purified via peptide column.

Immunogen: ZBTB5 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ZBTB6. The immunogen is located within the last 50 amino acids of ZBTB5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ZTBT5 antibody can be used for detection of ZTBT5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ZBTB5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ZBTB5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ZBTB5

Target: ZBTB5 (Zinc Finger and BTB Domain Containing 5 (ZBTB5))

Andere Bezeichnung: ZBTB5

Hintergrund: ZBTB5 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.

Gen-ID: 9925

NCBI Accession: NP_055687

UniProt: O15062