ZNF521 Antikörper (C-Term)

Produktnummer ABIN6991449

Dieses Anti-ZNF521-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZNF521 in ELISA und IHC (p). Geeignet für Human.

Kurzübersicht für ZNF521 Antikörper (C-Term) (ABIN6991449)

Target: ZNF521 (Zinc Finger Protein 521 (ZNF521))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF521 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ZNF521 Antikörper

Bindungsspezifität: AA 1160-1210, C-Term

Spezifität: ZNF521 antibody is human specific.

Aufreinigung: ZNF521 Antibody is affinity chromatography purified via peptide column.

Immunogen: ZNF521 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human ZNF521. The immunogen is located within amino acids 1160 - 1210 of ZNF521.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ZNF521 antibody can be used for detection of ZNF521 by immunohistochemistry at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ZNF521 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ZNF521 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ZNF521

Target: ZNF521 (Zinc Finger Protein 521 (ZNF521))

Andere Bezeichnung: ZNF521

Hintergrund: ZNF521 Antibody: The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.

Gen-ID: 25925

NCBI Accession: NP_056276

UniProt: Q96K83