TMEM59 Antikörper (N-Term)

Produktnummer ABIN6991448

Produktdetails anti-TMEM59 Antikörper

Target: TMEM59 (Transmembrane Protein 59 (TMEM59))

Bindungsspezifität: AA 80-130, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM59 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: TMEM59 Antibody is affinity chromatography purified via peptide column.

Immunogen: TMEM59 antibody was raised against a 16 amino acid synthetic peptide near amino terminus of human TMEM59. The immunogen is located within amino acids 80 - 130 of TMEM59.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TMEM59 antibody can be used for detection of TMEM59 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TMEM59 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TMEM59 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TMEM59

Target: TMEM59 (Transmembrane Protein 59 (TMEM59))

Andere Bezeichnung: TMEM59 (TMEM59 Produkte)

Synonyme: Tmem59 antikoerper, C1orf8 antikoerper, HSPC001 antikoerper, 1110001M20Rik antikoerper, 3110046P06Rik antikoerper, AI256529 antikoerper, D4Ertd20e antikoerper, MTDCF1 antikoerper, ORF18 antikoerper, transmembrane protein 59 antikoerper, tmem59 antikoerper, Tmem59 antikoerper, TMEM59 antikoerper

Hintergrund: TMEM59 Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.

Gen-ID: 9528

NCBI Accession: NP_004863

UniProt: Q9BXS4