SYNPO Antikörper (C-Term)

Produktnummer ABIN6991442

Der Kaninchen Polyklonal Anti-SYNPO-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, SYNPO in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SYNPO Antikörper (C-Term) (ABIN6991442)

Target: SYNPO (Synaptopodin (SYNPO))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNPO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SYNPO Antikörper

Bindungsspezifität: C-Term

Spezifität: At least three isoforms of SYNPO are known to exist, this antibody will detect all three isoforms. SYNPO antibody is predicted to not cross-react with other SYNPO family member proteins.

Aufreinigung: SYNPO Antibody is affinity chromatography purified via peptide column.

Immunogen: SYNPO antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SYNPO. The immunogen is located within the last 50 amino acids of SYNPO.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SYNPO antibody can be used for detection of SYNPO by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SYNPO Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SYNPO antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SYNPO

Target: SYNPO (Synaptopodin (SYNPO))

Andere Bezeichnung: SYNPO

Hintergrund: SYNPO Antibody: SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.

Molekulargewicht: Predicted: 75, 99, 102 kDa

Observed: 95 kDa

Gen-ID: 11346

NCBI Accession: NP_001159680

UniProt: Q8N3V7