PAPPA2 Antikörper (N-Term)

Produktnummer ABIN6991429

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PAPPA2 in WB, ICC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für PAPPA2 Antikörper (N-Term) (ABIN6991429)

Target: PAPPA2 (Pappalysin 2 (PAPPA2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAPPA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)

Produktdetails anti-PAPPA2 Antikörper

Bindungsspezifität: AA 450-500, N-Term

Aufreinigung: PLAC3 Antibody is affinity chromatography purified via peptide column.

Immunogen: PLAC3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human PLAC3. The immunogen is located within amino acids 450 - 500 of PLAC3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PLAC3 antibody can be used for detection of PLAC3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PLAC3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PLAC3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PAPPA2

Target: PAPPA2 (Pappalysin 2 (PAPPA2))

Andere Bezeichnung: PLAC3

Hintergrund: PLAC3 Antibody: PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.

Gen-ID: 60676

NCBI Accession: NP_064714

UniProt: Q9BXP8