NLRX1 Antikörper (N-Term)

Produktnummer ABIN6991399

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NLRX1 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für NLRX1 Antikörper (N-Term) (ABIN6991399)

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NLRX1 Antikörper

Bindungsspezifität: AA 70-120, N-Term

Aufreinigung: NOD5 Antibody is affinity chromatography purified via peptide column.

Immunogen: NOD5 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NOD5. The immunogen is located within amino acids 70 - 120 of NOD5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NOD5 antibody can be used for detection of NOD5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NOD5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NOD5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu NLRX1

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Andere Bezeichnung: NOD5

Hintergrund: NOD5 Antibody: NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-κ,B and JNK pathways by inducing reactive oxygen species production.

Gen-ID: 79671

NCBI Accession: NP_078894

UniProt: Q86UT6

Pathways: SARS-CoV-2 Protein Interaktom