CCDC106 Antikörper (C-Term)

Produktnummer ABIN6991384

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CCDC106 in ELISA, WB, IHC (p) und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CCDC106 Antikörper (C-Term) (ABIN6991384)

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC106 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-CCDC106 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: CCDC106 Antibody is affinity chromatography purified via peptide column.

Immunogen: CCDC106 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CCDC106. The immunogen is located within the last 50 amino acids of CCDC106.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CCDC106 antibody can be used for detection of CCDC106 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CCDC106 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CCDC106 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CCDC106

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Andere Bezeichnung: CCDC106

Hintergrund: CCDC106 Antibody: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.

Gen-ID: 29903

NCBI Accession: NP_037433

UniProt: Q9BWC9