Calneuron 1 Antikörper (N-Term)

Produktnummer ABIN6991382

Der Kaninchen Polyklonal Anti-Calneuron 1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Calneuron 1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Calneuron 1 Antikörper (N-Term) (ABIN6991382)

Target: Calneuron 1 (CALN1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calneuron 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Calneuron 1 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: CaBP8 Antibody is affinity chromatography purified via peptide column.

Immunogen: CaBP8 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CaBP8. The immunogen is located within the first 50 amino acids of CaBP8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CaBP8 antibody can be used for detection of CaBP8 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CaBP8 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CaBP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Calneuron 1

Target: Calneuron 1 (CALN1)

Andere Bezeichnung: CaBP8

Hintergrund: CaBP8 Antibody: Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70 % homology with CaBP7 and 50 % homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Gen-ID: 83698

NCBI Accession: NP_113656

UniProt: Q9BXU9