CABP7 Antikörper (N-Term)

Produktnummer ABIN6991381

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CABP7 in WB, ELISA, ICC und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für CABP7 Antikörper (N-Term) (ABIN6991381)

Target: CABP7 (Calcium Binding Protein 7 (CABP7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CABP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-CABP7 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: CaBP7 Antibody is affinity chromatography purified via peptide column.

Immunogen: CaBP7 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CaBP7. The immunogen is located within the first 50 amino acids of CaBP7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CaBP7 antibody can be used for detection of CaBP7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 4 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CaBP7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CaBP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CABP7

Target: CABP7 (Calcium Binding Protein 7 (CABP7))

Andere Bezeichnung: CaBP7

Hintergrund: CaBP7 Antibody: Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70 % homology with CaBP8 and 50 % homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Gen-ID: 164633

NCBI Accession: NP_872333

UniProt: Q86V35