TCTN3 Antikörper (C-Term)

Produktnummer ABIN6991371

Dieses Anti-TCTN3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TCTN3 in WB, ELISA, IF und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für TCTN3 Antikörper (C-Term) (ABIN6991371)

Target: TCTN3 (Tectonic Family Member 3 (TCTN3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCTN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TCTN3 Antikörper

Bindungsspezifität: AA 540-590, C-Term

Aufreinigung: TCTN3 Antibody is affinity chromatography purified via peptide column.

Immunogen: TCTN3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TCTN3. The immunogen is located within amino acids 540 - 590 of TCTN3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TCTN3 antibody can be used for detection of TCTN3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 4 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TCTN3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TCTN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TCTN3

Target: TCTN3 (Tectonic Family Member 3 (TCTN3))

Andere Bezeichnung: TCTN3

Hintergrund: TCTN3 Antibody: TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58 % similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.

Gen-ID: 26123

NCBI Accession: NP_056446

UniProt: Q6NUS6