SIRT7 Antikörper (N-Term)

Produktnummer ABIN6991348

Dieses Huhn Polyklonal-Antikörper erkennt spezifisch SIRT7 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für SIRT7 Antikörper (N-Term) (ABIN6991348)

Target: SIRT7 (Sirtuin 7 (SIRT7))

Reaktivität: Human, Ratte, Maus

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser SIRT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SIRT7 Antikörper

Bindungsspezifität: AA 50-100, N-Term

Aufreinigung: SIRT7 Antibody is affinity chromatography purified via peptide column.

Immunogen: SIRT7 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SIRT7. The immunogen is located within amino acids 50 - 100 of SIRT7.

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: SIRT7 antibody can be used for detection of SIRT7 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SIRT7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SIRT7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SIRT7

Target: SIRT7 (Sirtuin 7 (SIRT7))

Andere Bezeichnung: SIRT7

Hintergrund: SIRT7 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT7 is a nucleolar protein that positively regulates RNA polymerase I transcription and has been postulated to enable cells to sustain critical functions by inhibiting cell growth under severe stress conditions.

Gen-ID: 51547

NCBI Accession: NP_057622

UniProt: Q9NRC8