SAE1 Antikörper (C-Term)

Produktnummer ABIN6991336

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SAE1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SAE1 Antikörper (C-Term) (ABIN6991336)

Target: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SAE1 Antikörper

Bindungsspezifität: AA 240-290, C-Term

Aufreinigung: SAE1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SAE1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human SAE1. The immunogen is located within amino acids 240 - 290 of SAE1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SAE1 antibody can be used for detection of SAE1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SAE1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SAE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SAE1

Target: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Andere Bezeichnung: SAE1

Hintergrund: SAE1 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (SUMO-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. This sumoylation is effected by the heterodimeric enzyme SAE1/SAE2 and the SUMO-1-conjugating enzyme Ubch9. The sumoylation pathway mediated by SAE1/SAE2 is distinct from other ubiquitin-like protein (Ubl) pathways.

Molekulargewicht: Predicted: 38 kDa

Observed: 39 kDa

Gen-ID: 10055

NCBI Accession: NP_005491

UniProt: Q9UBE0