ANAPC13 Antikörper

Produktnummer ABIN6991331

Der Kaninchen Polyklonal Anti-ANAPC13-Antikörper wurde für ELISA, WB und IF validiert. Er ist geeignet, ANAPC13 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ANAPC13 Antikörper (ABIN6991331)

Target: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC13 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-ANAPC13 Antikörper

Aufreinigung: APC13 Antibody is affinity chromatography purified via peptide column.

Immunogen: APC13 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC13. The immunogen is located within the last 50 amino acids of APC13.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: APC13 antibody can be used for detection of APC13 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: APC13 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: APC13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ANAPC13

Target: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Andere Bezeichnung: APC13

Hintergrund: APC13 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.

Molekulargewicht: Predicted: 15 kDa

Observed: 14 kDa

Gen-ID: 25847

NCBI Accession: NP_056206

UniProt: Q9BS18