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MAEL Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAEL in ELISA, WB, IF und ICC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN6991303

Kurzübersicht für MAEL Antikörper (C-Term) (ABIN6991303)

Target

Alle MAEL Antikörper anzeigen
MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Reaktivität

Human, Maus, Ratte

Wirt

  • 8
Kaninchen

Klonalität

  • 8
Polyklonal

Konjugat

  • 4
  • 2
  • 1
  • 1
Dieser MAEL Antikörper ist unkonjugiert

Applikation

  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 5
    • 2
    • 1
    AA 30-80, C-Term

    Aufreinigung

    Maelstrom Antibody is affinity chromatography purified via peptide column.

    Immunogen

    Maelstrom antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human Maelstrom. The immunogen is located within amino acids 30 - 80 of Maelstrom.

    Isotyp

    IgG
  • Applikationshinweise

    Maelstrom antibody can be used for detection of Maelstrom by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Maelstrom Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    Maelstrom antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

    Andere Bezeichnung

    Maelstrom

    Hintergrund

    Maelstrom Antibody: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

    Gen-ID

    84944

    UniProt

    Q96JY0
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