LRRC19 Antikörper (C-Term)

Produktnummer ABIN6991292

Der Kaninchen Polyklonal Anti-LRRC19-Antikörper wurde für ELISA, WB, IF und ICC validiert. Er ist geeignet, LRRC19 in Proben von Human und Maus zu detektieren.

Kurzübersicht für LRRC19 Antikörper (C-Term) (ABIN6991292)

Target: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC19 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-LRRC19 Antikörper

Bindungsspezifität: AA 290-340, C-Term

Aufreinigung: LRRC19 Antibody is affinity chromatography purified via peptide column.

Immunogen: LRRC19 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRC19. The immunogen is located within amino acids 290 - 340 of LRRC19.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LRRC19 antibody can be used for detection of LRRC19 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LRRC19 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LRRC19 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LRRC19

Target: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Andere Bezeichnung: LRRC19

Hintergrund: LRRC19 Antibody: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-κ,B and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.

Gen-ID: 64922

NCBI Accession: NP_075052

UniProt: Q9H756