DCLK3 Antikörper (N-Term)

Produktnummer ABIN6991289

Der Kaninchen Polyklonal Anti-DCLK3-Antikörper wurde für ELISA, WB, IHC (p) und IF validiert. Er ist geeignet, DCLK3 in Proben von Human und Maus zu detektieren.

Kurzübersicht für DCLK3 Antikörper (N-Term) (ABIN6991289)

Target: DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCLK3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-DCLK3 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: DCLK3 Antibody is affinity chromatography purified via peptide column.

Immunogen: DCLK3 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human DCLK3. The immunogen is located within the last 50 amino acids of DCLK3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DCLK3 antibody can be used for detection of DCLK3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DCLK3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DCLK3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DCLK3

Target: DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))

Andere Bezeichnung: DCLK3

Hintergrund: DCLK3 Antibody: DCLK3 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK3 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK3 transcripts are present in liver and kidney, suggesting that DCLK3 may play other roles than in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization.

Gen-ID: 85443

NCBI Accession: NP_208382

UniProt: Q9C098