SLFN12 Antikörper (C-Term)

Produktnummer ABIN6991244

Der Kaninchen Polyklonal Anti-SLFN12-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, SLFN12 in Proben von Human zu detektieren.

Kurzübersicht für SLFN12 Antikörper (C-Term) (ABIN6991244)

Target: SLFN12 (Schlafen Family Member 12 (SLFN12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLFN12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SLFN12 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: SLFN12 Antibody is affinity chromatography purified via peptide column.

Immunogen: SLFN12 antibody was raised against a 12 amino acid synthetic peptide from near the carboxy terminus human SLFN12. The immunogen is located within the last 50 amino acids of SLFN12.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SLFN12 antibody can be used for detection of SLFN12 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SLFN12 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SLFN12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SLFN12

Target: SLFN12 (Schlafen Family Member 12 (SLFN12))

Andere Bezeichnung: SLFN12

Hintergrund: SLFN12 Antibody: Despite being first described several years ago, the roles of the Schlafen (SLFN) family of proteins remain largely unknown. The SLFN genes are preferentially expressed in lymphoid tissues and differentially regulated during thymocyte maturation. It is thought that many play roles in cell growth, hemopoietic cell differentiation, and T cell development and maturation. Most members contain at least one divergent AAA domain (AAA_4) that may play a role in ATP binding. Although also known as SLFN3, a Schlafen family member that may be a marker of T cell activation, human SLFN12 has relatively low homology to SLFN3 in other species. Loss of the SLFN12 gene due to deletion is associated with Kabuki syndrome, a multiple congenital anomaly syndrome, suggesting SLFN may play a role in this genetic condition.

Gen-ID: 55106

NCBI Accession: NP_060512

UniProt: Q8IYM2