SRPX Antikörper (N-Term)

Produktnummer ABIN6991220

Der Kaninchen Polyklonal Anti-SRPX Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, SRPX in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SRPX Antikörper (N-Term) (ABIN6991220)

Target: SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRPX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SRPX Antikörper

Bindungsspezifität: AA 30-80, N-Term

Aufreinigung: SRPX1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SRPX1 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human SRPX1. The immunogen is located within amino acids 30 - 80 of SRPX1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SRPX1 antibody can be used for detection of SRPX1 by Western blot at 0.25 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SRPX1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SRPX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SRPX

Target: SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))

Andere Bezeichnung: SRPX1

Hintergrund: SRPX1 Antibody: SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.

Gen-ID: 8406

NCBI Accession: NP_006298

UniProt: P78539