Anoctamin 2 Antikörper (N-Term)

Produktnummer ABIN6991200

Dieses Anti-Anoctamin 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Anoctamin 2 in WB, ELISA, IF und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für Anoctamin 2 Antikörper (N-Term) (ABIN6991200)

Target: Anoctamin 2 (ANO2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Anoctamin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Anoctamin 2 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: TMEM16B Antibody is affinity chromatography purified via peptide column.

Immunogen: TMEM16B antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human TMEM16B. The immunogen is located within the first 50 amino acids of TMEM16B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TMEM16B antibody can be used for detection of TMEM16B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TMEM16B Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TMEM16B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Anoctamin 2

Target: Anoctamin 2 (ANO2)

Andere Bezeichnung: TMEM16B

Hintergrund: TMEM16B Antibody: Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC's but has different biophysical characteristics such as voltage dependence and unitary conductance.

Molekulargewicht: Predicted: 110 kDa

Observed: 107 kDa

Gen-ID: 57101

NCBI Accession: NP_001265525

UniProt: Q9NQ90