RUSC2 Antikörper (C-Term)

Produktnummer ABIN6991196

Der Kaninchen Polyklonal Anti-RUSC2-Antikörper wurde für ELISA und IHC (p) validiert. Er ist geeignet, RUSC2 in Proben von Human zu detektieren.

Kurzübersicht für RUSC2 Antikörper (C-Term) (ABIN6991196)

Target: RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUSC2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RUSC2 Antikörper

Bindungsspezifität: AA 1410-1460, C-Term

Spezifität: At least three isoforms are known to exist, this antibody will only detect the longest isoform. This antibody is predicted to not cross-react with RUSC1.

Aufreinigung: RUSC2 Antibody is affinity chromatography purified via peptide column.

Immunogen: RUSC2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RUSC2. The immunogen is located within amino acids 1410 - 1460 of RUSC2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RUSC2 antibody can be used for detection of RUSC2 by immunohistrochemistry at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RUSC2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RUSC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RUSC2

Target: RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))

Andere Bezeichnung: RUSC2

Hintergrund: RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30 % amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.

Gen-ID: 9853

NCBI Accession: NP_001098673

UniProt: Q8N2Y8