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JMJD1C Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-JMJD1C-Antikörper wurde für ELISA, WB, IHC (p) und IF validiert. Er ist geeignet, JMJD1C in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN6991178

Kurzübersicht für JMJD1C Antikörper (N-Term) (ABIN6991178)

Target

Alle JMJD1C Antikörper anzeigen
JMJD1C (Jumonji Domain Containing 1C (JMJD1C))

Reaktivität

  • 13
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 10
  • 3
Kaninchen

Klonalität

  • 10
  • 3
Polyklonal

Konjugat

  • 9
  • 2
  • 1
  • 1
Dieser JMJD1C Antikörper ist unkonjugiert

Applikation

  • 7
  • 7
  • 4
  • 3
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 380-430, N-Term

    Spezifität

    This antibody will not cross-react with JMJD1A or JMJD1B.

    Aufreinigung

    JMJD1C Antibody is affinity chromatography purified via peptide column.

    Immunogen

    JMJD1C antibody was raised against a 20 amino acid synthetic peptide from near the amino terminus of human JMJD1C. The immunogen is located within amino acids 380 - 430 of JMJD1C.

    Isotyp

    IgG
  • Applikationshinweise

    JMJD1C antibody can be used for detection of JMJD1C by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    JMJD1C Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    JMJD1C antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    JMJD1C (Jumonji Domain Containing 1C (JMJD1C))

    Andere Bezeichnung

    JMJD1C

    Hintergrund

    JMJD1C Antibody: The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.

    Gen-ID

    221037

    NCBI Accession

    NP_116165

    UniProt

    Q15652

    Pathways

    Nuclear Hormone Receptor Binding
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