PPPDE1 Antikörper (C-Term)

Produktnummer ABIN6991134

Dieses Anti-PPPDE1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PPPDE1 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PPPDE1 Antikörper (C-Term) (ABIN6991134)

Target: PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPPDE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PPPDE1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: PNAS4 Antibody is affinity chromatography purified via peptide column.

Immunogen: PNAS4 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PNAS4. The immunogen is located within the last 50 amino acids of PNAS4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PNAS4 antibody can be used for detection of PNAS4 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PNAS4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PNAS4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PPPDE1

Target: PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))

Andere Bezeichnung: PNAS4

Hintergrund: PNAS4 Antibody: PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist.

Gen-ID: 51029

NCBI Accession: NP_057160

UniProt: Q9BSY9