RGS21 Antikörper (AA 40-90)

Produktnummer ABIN6991130

Der Kaninchen Polyklonal Anti-RGS21-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, RGS21 in Proben von Human zu detektieren.

Kurzübersicht für RGS21 Antikörper (AA 40-90) (ABIN6991130)

Target: RGS21 (Regulator of G-Protein Signaling 21 (RGS21))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-RGS21 Antikörper

Bindungsspezifität: AA 40-90

Aufreinigung: RGS21 Antibody is affinity chromatography purified via peptide column.

Immunogen: RGS21 antibody was raised against a 16 amino acid synthetic peptide near the center of human RGS21. The immunogen is located within amino acids 40 - 90 of RGS21.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RGS21 antibody can be used for detection of RGS21 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RGS21 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RGS21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RGS21

Target: RGS21 (Regulator of G-Protein Signaling 21 (RGS21))

Andere Bezeichnung: RGS21

Hintergrund: RGS21 Antibody: Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors. Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes.

Gen-ID: 431704

NCBI Accession: NP_001034241

UniProt: Q2M5E4

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling