MC4R Antikörper (N-Term)
-
- Target Alle MC4R Antikörper anzeigen
- MC4R (Melanocortin 4 Receptor (MC4R))
-
Bindungsspezifität
- N-Term
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser MC4R Antikörper ist unkonjugiert
-
Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Aufreinigung
- MC4R Antibody is affinity chromatography purified via peptide column.
- Immunogen
- MC4R antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human MC4R. The immunogen is located within the first 50 amino acids of MC4R.
- Isotyp
- IgG
- Top Product
- Discover our top product MC4R Primärantikörper
-
-
- Applikationshinweise
-
MC4R antibody can be used for detection of MC4R by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- MC4R Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- MC4R antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
- Target
- MC4R (Melanocortin 4 Receptor (MC4R))
- Andere Bezeichnung
- MC4R (MC4R Produkte)
- Synonyme
- zMC4 antikoerper, si:dkey-151m6.62 antikoerper, mc4r antikoerper, MC4R antikoerper, LOC100218148 antikoerper, Mc4-r antikoerper, melanocortin 4 receptor antikoerper, mc4r antikoerper, MC4R antikoerper, Mc4r antikoerper
- Hintergrund
- MC4R Antibody: The melanocortin-4 receptor (MC4R) is a member of the superfamily of seven transmembrane G-protein coupled receptors that are involved in multiple signal transduction pathways including the cAMP and MAPK signaling pathways. It is thought that the melanocortin system modulates energy expenditure and insulin sensitivity, activation of the MC4R results in the inhibition of c-Jun N-terminal kinase (JNK) activity and promotes insulin signaling. MC4R-null mice display maturity onset obesity characterized by hyperphagia, increased adiposity, hyperinsulinaemia and hyperleptinaemia, suggesting that like other obesity-linked genes such as FTO, PTER, and NPC1, MC4R is a potential candidate target for the treatment of obesity.
- Gen-ID
- 4160
- NCBI Accession
- NP_005903
- UniProt
- P32245
- Pathways
- Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
-