TTR Antikörper (AA 40-90)

Produktnummer ABIN6991113

Dieses Anti-TTR-Antikörper ist ein Huhn Polyklonal-Antikörper zur Detektion von TTR in WB, ELISA, IF und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für TTR Antikörper (AA 40-90) (ABIN6991113)

Target: TTR (Transthyretin (TTR))

Reaktivität: Human, Maus, Ratte

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser TTR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TTR Antikörper

Bindungsspezifität: AA 40-90

Aufreinigung: Transthyretin Antibody is affinity chromatography purified via peptide column.

Immunogen: Transthyretin antibody was raised against a 17 amino acid synthetic peptide near the center of human Transthyretin. The immunogen is located within amino acids 40 - 90 of Transthyretin.

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: Transthyretin antibody can be used for detection of Transthyretin by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Transthyretin Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Transthyretin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TTR

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: Transthyretin

Hintergrund: Transthyretin Antibody: Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson's disease, schizophrenia, and depression.

Molekulargewicht: Predicted: 15 kDa

Observed: 16 kDa

Gen-ID: 7276

UniProt: P02766

Pathways: Hormone Transport