Matrilin 3 Antikörper (AA 180-230)

Produktnummer ABIN6991105

Produktdetails anti-Matrilin 3 Antikörper

Target: Matrilin 3 (MATN3)

Bindungsspezifität: AA 180-230

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Matrilin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Aufreinigung: MATN3 Antibody is affinity chromatography purified via peptide column.

Immunogen: MATN3 antibody was raised against a 13 amino acid synthetic peptide from near the center of human MATN3. The immunogen is located within amino acids 180 - 230 of MATN3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: MATN3 antibody can be used for detection of MATN3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: MATN3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: MATN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Matrilin 3

Target: Matrilin 3 (MATN3)

Andere Bezeichnung: MATN3 (MATN3 Produkte)

Synonyme: DIPOA antikoerper, EDM5 antikoerper, HOA antikoerper, OADIP antikoerper, OS2 antikoerper, AV009181 antikoerper, matrilin 3 antikoerper, MATN3 antikoerper, Matn3 antikoerper

Hintergrund: MATN3 Antibody: Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.

Gen-ID: 4148

UniProt: O15232