MTCH2 Antikörper (N-Term)
Kurzübersicht für MTCH2 Antikörper (N-Term) (ABIN6991074)
Target
Alle MTCH2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 80-130, N-Term
-
Aufreinigung
- MTCH2 Antibody is affinity chromatography purified via peptide column.
-
Immunogen
- MTCH2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MTCH2. The immunogen is located within amino acids 80 - 130 of MTCH2.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
MTCH2 antibody can be used for detection of MTCH2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- MTCH2 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C,4 °C
-
Informationen zur Lagerung
- MTCH2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- MTCH2 (Mitochondrial Carrier 2 (MTCH2))
-
Andere Bezeichnung
- MTCH2
-
Hintergrund
- MTCH2 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.
-
Gen-ID
- 56428
-
NCBI Accession
- NP_055157
-
UniProt
- Q791V5
Target
-