CRMP1 Antikörper (N-Term)

Produktnummer ABIN6991044

Dieses Anti-CRMP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CRMP1 in WB, ELISA, IHC (p) und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CRMP1 Antikörper (N-Term) (ABIN6991044)

Target: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-CRMP1 Antikörper

Bindungsspezifität: AA 90-140, N-Term

Spezifität: This antibody is expected to recognize only the longest isoform of CRMP-1.

Aufreinigung: CRMP1 Antibody is affinity chromatography purified via peptide column.

Immunogen: CRMP1 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human CRMP1. The immunogen is located within amino acids 90 - 140 of CRMP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CRMP1 antibody can be used for the detection of CRMP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CRMP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CRMP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CRMP1

Target: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Andere Bezeichnung: CRMP1

Hintergrund: CRMP1 Antibody: Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain, later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.

Gen-ID: 1400

NCBI Accession: NP_001014809

UniProt: Q14194