CERS6 Antikörper (C-Term)

Produktnummer ABIN6991026

Dieses Anti-CERS6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CERS6 in ELISA, WB, IHC (p) und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CERS6 Antikörper (C-Term) (ABIN6991026)

Target: CERS6 (Ceramide Synthase 6 (CERS6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CERS6 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-CERS6 Antikörper

Bindungsspezifität: C-Term

Spezifität: At least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.

Aufreinigung: LASS6 Antibody is affinity chromatography purified via peptide column.

Immunogen: LASS6 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human LASS6. The immunogen is located within the last 50 amino acids of LASS6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LASS6 antibody can be used for detection of LASS6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LASS6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LASS6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CERS6

Target: CERS6 (Ceramide Synthase 6 (CERS6))

Andere Bezeichnung: LASS6

Hintergrund: LASS6 Antibody: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development.

Gen-ID: 253782

UniProt: Q6ZMG9