IL-17 Antikörper (N-Term)

Produktnummer ABIN6991007

Der Kaninchen Polyklonal Anti-IL-17-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, IL-17 in Proben von Human und Maus zu detektieren.

Kurzübersicht für IL-17 Antikörper (N-Term) (ABIN6991007)

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IL-17 Antikörper

Bindungsspezifität: AA 40-90, N-Term

Aufreinigung: IL-17 Antibody is affinity chromatography purified via peptide column.

Immunogen: IL-17 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human IL-17A. The immunogen is located within amino acids 40 - 90 of IL-17.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 0.125-4 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IL-17 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IL-17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu IL-17

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Andere Bezeichnung: IL-17

Hintergrund: IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κ,B and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.

Molekulargewicht: Predicted: 17.5kD

Observed: 20 kD (Post-modification: 1 N-linked glycosylation) kDa

Gen-ID: 3605

NCBI Accession: NP_002181

UniProt: Q16552