SPRED3 Antikörper (AA 140-190)

Produktnummer ABIN6990998

Der Kaninchen Polyklonal Anti-SPRED3-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, SPRED3 in Proben von Human zu detektieren.

Kurzübersicht für SPRED3 Antikörper (AA 140-190) (ABIN6990998)

Target: SPRED3 (Sprouty-Related, EVH1 Domain Containing 3 (SPRED3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPRED3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-SPRED3 Antikörper

Bindungsspezifität: AA 140-190

Spezifität: This Spred3 antibody is predicted to have no cross-reactivity to Spred1 or Spred2.

Aufreinigung: Spred3 Antibody is affinity chromatography purified via peptide column.

Immunogen: Spred3 antibody was raised against a 16 amino acid synthetic peptide near the center of the human Spred3. The immunogen is located within amino acids 140 - 190 of Spred3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Spred3 antibody can be used for detection of Spred3 by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Spred3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Spred3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SPRED3

Target: SPRED3 (Sprouty-Related, EVH1 Domain Containing 3 (SPRED3))

Andere Bezeichnung: Spred3

Hintergrund: Spred3 Antibody: Spred3 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1 and Spred2, Spred3 contains and EVH1 domain in its amino terminus and a Sprouty-related cysteine-rich (SPR) domain in its C-terminus, but does not possess a functional c-kit binding domain (KBD). The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Although Spred3 was initially reported to be expressed in brain, at least one report also indicates that Spred3 can be found in liver. At least two isoforms of Spred3 are known to exist.

Molekulargewicht: Predicted: 45 kDa

Observed: 45 kDa

Gen-ID: 399473

NCBI Accession: NP_001035987

UniProt: Q2MJR0