ALDH5A1 Antikörper (C-Term)

Produktnummer ABIN6990982

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ALDH5A1 in ELISA und WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für ALDH5A1 Antikörper (C-Term) (ABIN6990982)

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDH5A1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-ALDH5A1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Aldh5A1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Aldh5A1 antibody was raised against a 22 amino acid synthetic peptide near the carboxy terminus of the human Aldh5A1. The immunogen is located within the last 50 amino acids of Aldh5A1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Aldh5A1 antibody can be used for detection of Aldh5A1 by Western blot at 0.25 - 0.5 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Aldh5A1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Aldh5A1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ALDH5A1

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Andere Bezeichnung: Aldh5A1

Hintergrund: Aldh5A1 Antibody: Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.

Molekulargewicht: Predicted: 60 kDa

Observed: 60 kDa

Gen-ID: 7915

NCBI Accession: NP_733936

UniProt: P51649

Pathways: Monocarboxylic Acid Catabolic Process