Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

POFUT1 Antikörper (N-Term)

This anti-POFUT1 antibody (ABIN6990964) is a Rabbit Polyclonal antibody detecting POFUT1 in WB, ELISA, IHC (p). Suitable for Human, Mouse.
Produktnummer ABIN6990964

Quick Overview for POFUT1 Antikörper (N-Term) (ABIN6990964)

Target

Alle POFUT1 Antikörper anzeigen
POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))

Reaktivität

  • 39
  • 11
  • 8
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus

Wirt

  • 39
  • 2
Kaninchen

Klonalität

  • 38
  • 2
Polyklonal

Konjugat

  • 31
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser POFUT1 Antikörper ist unkonjugiert

Applikation

  • 32
  • 25
  • 17
  • 9
  • 9
  • 6
  • 6
  • 6
  • 4
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 90-140, N-Term

    Spezifität

    At least two isoforms of POFUT1 are known to exist. This antibody is predicted to not cross-react with POFUT2.

    Aufreinigung

    POFUT1 Antibody is affinity chromatography purified via peptide column.

    Immunogen

    POFUT1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human POFUT1. The immunogen is located within amino acids 90 - 140 of POFUT1.

    Isotyp

    IgG
  • Applikationshinweise

    POFUT1 antibody can be used for the detection of POFUT1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    POFUT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    POFUT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))

    Andere Bezeichnung

    POFUT1

    Hintergrund

    POFUT1 Antibody: POFUT1, an endoplasmic reticulum-residing member of the glycosyltransferase O-Fuc family, adds O-fucose through an O-glycosidic linkage to conserved serine or threonines in epidermal growth factor-like repeats of several cell surface and secreted proteins. Unlike its homolog POFUT2, POFUT1 can also catalyze the transfer of fucose to thrombospondin type 1 repeats. Many of the substrates of POFUT1 are involved in ligand-induced receptor signaling. One such protein is Notch, mouse ES cells lacking POFUT have normal levels of Notch receptors at the cell surface, but these receptors do not bind Notch ligands or exhibit Notch signaling.

    Gen-ID

    23509

    NCBI Accession

    NP_056167

    UniProt

    Q9H488

    Pathways

    Notch Signalweg, SARS-CoV-2 Protein Interaktom
Sie sind hier:
Chat with us!