POFUT1 Antikörper (N-Term)

Produktnummer ABIN6990964

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch POFUT1 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für POFUT1 Antikörper (N-Term) (ABIN6990964)

Target: POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POFUT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-POFUT1 Antikörper

Bindungsspezifität: AA 90-140, N-Term

Spezifität: At least two isoforms of POFUT1 are known to exist. This antibody is predicted to not cross-react with POFUT2.

Aufreinigung: POFUT1 Antibody is affinity chromatography purified via peptide column.

Immunogen: POFUT1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human POFUT1. The immunogen is located within amino acids 90 - 140 of POFUT1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: POFUT1 antibody can be used for the detection of POFUT1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: POFUT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: POFUT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu POFUT1

Target: POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))

Andere Bezeichnung: POFUT1

Hintergrund: POFUT1 Antibody: POFUT1, an endoplasmic reticulum-residing member of the glycosyltransferase O-Fuc family, adds O-fucose through an O-glycosidic linkage to conserved serine or threonines in epidermal growth factor-like repeats of several cell surface and secreted proteins. Unlike its homolog POFUT2, POFUT1 can also catalyze the transfer of fucose to thrombospondin type 1 repeats. Many of the substrates of POFUT1 are involved in ligand-induced receptor signaling. One such protein is Notch, mouse ES cells lacking POFUT have normal levels of Notch receptors at the cell surface, but these receptors do not bind Notch ligands or exhibit Notch signaling.

Gen-ID: 23509

NCBI Accession: NP_056167

UniProt: Q9H488

Pathways: Notch Signalweg, SARS-CoV-2 Protein Interaktom