NUP107 Antikörper (C-Term)

Produktnummer ABIN6990943

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NUP107 in WB, ELISA, IF und ICC. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für NUP107 Antikörper (C-Term) (ABIN6990943)

Target: NUP107 (Nucleoporin 107kDa (NUP107))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP107 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-NUP107 Antikörper

Bindungsspezifität: AA 820-870, C-Term

Aufreinigung: NUP107 Antibody is affinity chromatography purified via peptide column.

Immunogen: NUP107 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human NUP107. The immunogen is located within amino acids 820 - 870 of NUP107.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NUP107 antibody can be used for detection of NUP107 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NUP107 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NUP107 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu NUP107

Target: NUP107 (Nucleoporin 107kDa (NUP107))

Andere Bezeichnung: NUP107

Hintergrund: NUP107 Antibody: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.

Gen-ID: 57122

UniProt: P57740

Pathways: Protein targeting to Nucleus