GDF6 Antikörper (C-Term)

Produktnummer ABIN6990939

Dieses Anti-GDF6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GDF6 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für GDF6 Antikörper (C-Term) (ABIN6990939)

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GDF6 Antikörper

Bindungsspezifität: AA 320-370, C-Term

Aufreinigung: GDF6 Antibody is affinity chromatography purified via peptide column.

Immunogen: GDF6 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human GDF6. The immunogen is located within amino acids 320 - 370 of GDF6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GDF6 antibody can be used for detection of GDF6 by Western blot at 0.5 to 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GDF6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: GDF6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GDF6

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Andere Bezeichnung: GDF6

Hintergrund: GDF6 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.

Gen-ID: 392255

NCBI Accession: NP_001001557

UniProt: Q6KF10