BST2 Antikörper (N-Term)

Produktnummer ABIN6990931

Produktdetails anti-BST2 Antikörper

Target: BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

Bindungsspezifität: AA 60-110, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BST2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Bst2 Antibody is affinity chromatography purified via peptide column.

Immunogen: Bst2 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of the mouse Bst2. The immunogen is located within amino acids 60 - 110 of Bst2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Bst2 antibody can be used for detection of Bst2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Bst2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Bst2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu BST2

Target: BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

Andere Bezeichnung: Bst2 (BST2 Produkte)

Synonyme: BST2 antikoerper, CD317 antikoerper, TETHERIN antikoerper, 2310015I10Rik antikoerper, Bst-2 antikoerper, C87040 antikoerper, DAMP-1 antikoerper, GREG antikoerper, Damp1 antikoerper, bone marrow stromal cell antigen 2 antikoerper, bone marrow stromal antigen 2 antikoerper, BST2 antikoerper, LOC618737 antikoerper, Bst2 antikoerper

Hintergrund: Bst2 Antibody: Bst2 was first identified as a novel terminal B-cell-restricted antigen termed HM1.24 that is expressed on certain bone marrow cells as well as other tissues. The surface expression of Bst2 on fibroblast cell lines facilitated the stromal cell-dependent growth of DW34, a pre-B-cell line, suggesting that this protein is involved in pre-B-cell growth. Later experiments also showed it to be upregulated in several myeloma cells. More recently, Bst2 was identified an inhibitor of retroviral release from human cells whose activity is antagonized by the HIV-1 accessory protein Vpu. While Bst2 caused retention of virions on cell surfaces or endocytosis into Bst2-positive compartments, its depletion abolished the viral requirement for Vpu for virus release. This activity may represent a potential therapeutic strategy for the treatment of HIV/AIDS.

Gen-ID: 69550

UniProt: Q8R2Q8

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response