CLIP1 Antikörper (C-Term)

Produktnummer ABIN6990930

Produktdetails anti-CLIP1 Antikörper

Target: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Bindungsspezifität: AA 1340-1390, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Aufreinigung: CLIP170 Antibody is affinity chromatography purified via peptide column.

Immunogen: CLIP170 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human CLIP170. The immunogen is located within amino acids 1340 - 1390 of CLIP170.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CLIP170 antibody can be used for detection of CLIP170 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunoflourescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CLIP170 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CLIP170 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CLIP1

Target: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Andere Bezeichnung: CLIP170 (CLIP1 Produkte)

Synonyme: RSN antikoerper, CLIP1 antikoerper, clip170 antikoerper, clip-170 antikoerper, CLIP antikoerper, CLIP-170 antikoerper, CLIP170 antikoerper, CYLN1 antikoerper, 1110007I12Rik antikoerper, 4631429H07Rik antikoerper, AV017631 antikoerper, C81039 antikoerper, Clip50 antikoerper, Rsn antikoerper, mKIAA4046 antikoerper, restin antikoerper, CAP-Gly domain containing linker protein 1 antikoerper, CAP-Gly domain-containing linker protein 1 antikoerper, CAP-Gly domain containing linker protein 1 L homeolog antikoerper, CAP-GLY domain containing linker protein 1b antikoerper, CAP-GLY domain containing linker protein 1 antikoerper, CLIP1 antikoerper, LOC100075022 antikoerper, clip1 antikoerper, clip1.L antikoerper, clip1b antikoerper, Clip1 antikoerper

Hintergrund: CLIP170 Antibody: CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.

Gen-ID: 6249

NCBI Accession: NP_002947

UniProt: P30622

Pathways: Microtubule Dynamics