At least three isoforms of SAPAP2 are known to exist. This SAPAP2 antibody will not cross-react with other SAPAP proteins.
Aufreinigung
SAPAP2 Antibody is affinity chromatography purified via peptide column.
Immunogen
SAPAP2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human SAPAP2. The immunogen is located within amino acids 480 - 530 of SAPAP2.
DLGAP2
Reaktivität: Human, Ratte
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
Alexa Fluor 488
Applikationshinweise
SAPAP2 antibody can be used for detection of SAPAP2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
SAPAP2 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
SAPAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
DLGAP2
(Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))
PSD-95 antikoerper, DAP2 antikoerper, SAPAP2 antikoerper, 6430596N04Rik antikoerper, Sapap2 antikoerper, DLG associated protein 2 antikoerper, disks large-associated protein 2 antikoerper, discs, large (Drosophila) homolog-associated protein 2a antikoerper, discs, large (Drosophila) homolog-associated protein 2 antikoerper, DLGAP2 antikoerper, LOC463960 antikoerper, dlgap2a antikoerper, LOC100447448 antikoerper, Dlgap2 antikoerper
Hintergrund
SAPAP2 Antibody: SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP2 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies.