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Transportin 3 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-Transportin 3-Antikörper wurde für ELISA und WB validiert. Er ist geeignet, Transportin 3 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN6990902

Kurzübersicht für Transportin 3 Antikörper (N-Term) (ABIN6990902)

Target

Alle Transportin 3 (TNPO3) Antikörper anzeigen
Transportin 3 (TNPO3)

Reaktivität

  • 20
  • 14
  • 14
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 18
  • 2
Kaninchen

Klonalität

  • 11
  • 9
Polyklonal

Konjugat

  • 9
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Transportin 3 Antikörper ist unkonjugiert

Applikation

  • 8
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
ELISA, Western Blotting (WB)
  • Bindungsspezifität

    • 5
    • 1
    • 1
    • 1
    • 1
    AA 140-190, N-Term

    Aufreinigung

    TNPO3 Antibody is affinity chromatography purified via peptide column.

    Immunogen

    TNPO3 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human TNPO3. The immunogen is located within amino acids 140 - 190 of TNPO3.

    Isotyp

    IgG
  • Applikationshinweise

    TNPO3 antibody can be used for detection of TNPO3 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    TNPO3 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    TNPO3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    Transportin 3 (TNPO3)

    Andere Bezeichnung

    TNPO3

    Hintergrund

    TNPO3 Antibody: TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins. Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated. More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment. At least three isoforms of TNPO3 are known to exist.

    Molekulargewicht

    Predicted: 105 kDa

    Observed: 99 kDa

    Gen-ID

    23534

    UniProt

    Q9Y5L0

    Pathways

    Protein targeting to Nucleus
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