ELOVL6 Antikörper (N-Term)

Produktnummer ABIN6990894

Dieses Anti-ELOVL6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ELOVL6 in WB, ELISA, IHC (p) und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ELOVL6 Antikörper (N-Term) (ABIN6990894)

Target: ELOVL6 (ELOVL Fatty Acid Elongase 6 (ELOVL6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELOVL6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-ELOVL6 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: ELOVL6 Antibody is affinity chromatography purified via peptide column.

Immunogen: ELOVL6 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of the human ELOVL6. The immunogen is located within the first 50 amino acids of ELOVL6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELOVL6 antibody can be used for detection of ELOVL6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ELOVL6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ELOVL6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ELOVL6

Target: ELOVL6 (ELOVL Fatty Acid Elongase 6 (ELOVL6))

Andere Bezeichnung: ELOVL6

Hintergrund: ELOVL6 Antibody: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

Molekulargewicht: Predicted: 29 kDa

Observed: 28 kDa

Gen-ID: 79071

NCBI Accession: NP_076995

UniProt: Q9H5J4