BAIAP3 Antikörper (N-Term)

Produktnummer ABIN6990870

Dieses Anti-BAIAP3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BAIAP3 in ELISA, WB und IHC (p). Geeignet für Human.

Kurzübersicht für BAIAP3 Antikörper (N-Term) (ABIN6990870)

Target: BAIAP3 (BAI1-Associated Protein 3 (BAIAP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAIAP3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BAIAP3 Antikörper

Bindungsspezifität: AA 60-110, N-Term

Spezifität: BAP3 is known to have two isoforms, this BAP3 antibody will recognize only isoform 2. Lower molecular weight bands may represent cleavage or degradation products.

Aufreinigung: BAP3 Antibody is affinity chromatography purified via peptide column.

Immunogen: BAP3 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human BAP3. The immunogen is located within amino acids 60 - 110 of BAP3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: BAP3 antibody can be used for the detection of BAP3 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: BAP3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: BAP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu BAIAP3

Target: BAIAP3 (BAI1-Associated Protein 3 (BAIAP3))

Andere Bezeichnung: BAP3

Hintergrund: BAP3 Antibody: BAP3 was initially identified through interaction in a yeast two-hybrid system with the brain-specific angiogenesis inhibitor 1, a p53-target gene that encodes a seven-span transmembrane protein member of the secretin receptor family. BAP3 is predominantly expressed in the brain and possess high homology with Munc13 and synaptotagmin, suggesting that BAP3 may play a role in regulating neurotransmitter release. Recent experiments have shown that BAP3 is induced in certain tumors such as desmoplastic small round cell tumor. Ectopic expression of BAP3 in tumor cells dramatically enhances growth in low serum conditions and colony formation in soft agar, suggesting that the regulated exocytotic pathway may play a role in cancer cell proliferation.

Gen-ID: 8938

NCBI Accession: NP_001273393

UniProt: O94812