LGI2 Antikörper (N-Term)

Produktnummer ABIN6990865

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LGI2 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für LGI2 Antikörper (N-Term) (ABIN6990865)

Target: LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-LGI2 Antikörper

Bindungsspezifität: N-Term

Spezifität: This LGI2 antibody is predicted to be specific to LGI2 and not recognize other LGI proteins. Three isoforms of LGI2 are known to exist, this LGI2 antibody will recognize only the longest.

Aufreinigung: LGI2 Antibody is affinity chromatography purified via peptide column.

Immunogen: LGI2 antibody was raised against a 11 amino acid synthetic peptide from near the amino terminus of human LGI2. The immunogen is located within the first 50 amino acids of LGI2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LGI2 antibody can be used for the detection of LGI2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LGI2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LGI2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LGI2

Target: LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))

Andere Bezeichnung: LGI2

Hintergrund: LGI2 Antibody: The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.

Gen-ID: 246316

UniProt: Q8K4Z0, Q8N0V4