SLITRK1 Antikörper (AA 270-320)

Produktnummer ABIN6990850

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SLITRK1 in WB, ELISA, IHC (p) und IF. Er zeigt eine Reaktivität gegenüber Ratte, Human und Maus.

Kurzübersicht für SLITRK1 Antikörper (AA 270-320) (ABIN6990850)

Target: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLITRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-SLITRK1 Antikörper

Bindungsspezifität: AA 270-320

Spezifität: This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Aufreinigung: Slitrk1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Slitrk1 antibody was raised against a 18 amino acid synthetic peptide from near the center of human Slitrk1. The immunogen is located within amino acids 270 - 320 of Slitrk1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Slitrk1 antibody can be used for detection of Slitrk1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Slitrk1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Slitrk1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SLITRK1

Target: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Andere Bezeichnung: Slitrk1

Hintergrund: Slitrk1 Antibody: SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all.

Gen-ID: 114798

NCBI Accession: NP_443142

UniProt: Q96PX8