Cathelicidin Antikörper (AA 50-100)

Produktnummer ABIN6990841

Produktdetails anti-Cathelicidin Antikörper

Target: Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))

Bindungsspezifität: AA 50-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathelicidin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Cathelicidin Antibody is affinity chromatography purified via peptide column.

Immunogen: Cathelicidin antibody was raised against a 17 amino acid synthetic peptide near the center of the human Cathelicidin. The immunogen is located within amino acids 50 - 100 of Cathelicidin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Cathelicidin antibody can be used for detection of Cathelicidin by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Cathelicidin Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Cathelicidin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Cathelicidin

Target: Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))

Andere Bezeichnung: Cathelicidin (CAMP Produkte)

Synonyme: CAP-18 antikoerper, CAP18 antikoerper, CRAMP antikoerper, FALL-39 antikoerper, FALL39 antikoerper, LL37 antikoerper, CATH-2 antikoerper, Cnlp antikoerper, Cramp antikoerper, MCLP antikoerper, CATH-B1 antikoerper, CATHB1 antikoerper, CATHL2 antikoerper, CATHL7 antikoerper, CAP11 antikoerper, cathelicidin antimicrobial peptide antikoerper, CAMP antikoerper, LOC100136187 antikoerper, LOC100136439 antikoerper, Camp antikoerper

Hintergrund: Cathelicidin Antibody: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.

Molekulargewicht: Predicted: 19 kDa

Observed: 18 kDa

Gen-ID: 820

NCBI Accession: NP_004336

UniProt: P49913

Pathways: Cellular Response to Molecule of Bacterial Origin