TBC1D4 Antikörper (C-Term)

Produktnummer ABIN6990834

Der Kaninchen Polyklonal anti-TBC1D4 Antikörper (ABIN6990834) detektiert spezifisch TBC1D4 in ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TBC1D4 Antikörper (C-Term) (ABIN6990834)

Target: TBC1D4 (TBC1 Domain Family, Member 4 (TBC1D4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBC1D4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TBC1D4 Antikörper

Bindungsspezifität: AA 1190-1240, C-Term

Aufreinigung: TBC1D4 Antibody is affinity chromatography purified via peptide column.

Immunogen: TBC1D4 antibody was raised against an 19 amino acid peptide near the carboxy terminus of human TBC1D4 . The immunogen is located within amino acids 1190 - 1240 of TBC1D4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TBC1D4 antibody can be used for immunohistochemistry starting at 10 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TBC1D4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TBC1D4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu TBC1D4

Target: TBC1D4 (TBC1 Domain Family, Member 4 (TBC1D4))

Andere Bezeichnung: TBC1D4

Hintergrund: TBC1D4 Antibody: TBC1D4, also known as the Akt substrate AS160, was initially identified as an Akt substrate containing a GTPase-activating domain that regulates GLUT4 trafficking, with activation following insulin stimulation. TBC1D4 truncations in humans is a major cause of dominant inherited insulin resistance. The loss of TBC1D4 results in the accumulation of GLUT4 in compartments that are primed for fusion in basal adipocytes.

Molekulargewicht: Predicted: 143 kDa

Observed: 140 kDa

Gen-ID: 9882

NCBI Accession: NP_055647

UniProt: O60343