GRIK5 Antikörper (C-Term)

Produktnummer ABIN6990825

Produktdetails anti-GRIK5 Antikörper

Target: GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIK5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: This Grik5 antibody does not cross-react with Grik4.

Aufreinigung: Grik5 Antibody is affinity chromatography purified via peptide column.

Immunogen: Grik5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Grik5. The immunogen is located within the last 50 amino acids of Grik5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Grik5 antibody can be used for detection of Grik5 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Grik5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Grik5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GRIK5

Target: GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))

Andere Bezeichnung: Grik5 (GRIK5 Produkte)

Synonyme: EAA2 antikoerper, GRIK2 antikoerper, GluK5 antikoerper, KA2 antikoerper, GRIK5 antikoerper, Glur6 antikoerper, ka2 antikoerper, eaa2 antikoerper, GluRgamma2 antikoerper, iGlu5 antikoerper, glutamate ionotropic receptor kainate type subunit 5 antikoerper, glutamate receptor, ionotropic, kainate 5 antikoerper, glutamate ionotropic receptor kainate type subunit 2 antikoerper, glutamate receptor, ionotropic, kainate 5 L homeolog antikoerper, glutamate receptor, ionotropic, kainate 5 (gamma 2) antikoerper, GRIK5 antikoerper, GRIK2 antikoerper, grik5 antikoerper, grik5.L antikoerper, Grik5 antikoerper

Hintergrund: Grik5 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2. In Grik2- but not Grik1-null mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface.

Gen-ID: 2901

NCBI Accession: NP_002079

UniProt: Q16478

Pathways: Carbohydrate Homeostasis, Synaptic Membrane, Maintenance of Protein Location, Synaptic Vesicle Exocytosis